{"id":697,"date":"2024-04-30T08:37:13","date_gmt":"2024-04-30T06:37:13","guid":{"rendered":"https:\/\/sites.uef.fi\/bioinformatics\/?page_id=697"},"modified":"2026-10-19T13:02:34","modified_gmt":"2026-10-19T11:02:34","slug":"genomic-imputation-service","status":"publish","type":"page","link":"https:\/\/sites.uef.fi\/bioinformatics\/genomic-imputation-service\/","title":{"rendered":"Genomic Imputation Service"},"content":{"rendered":"\n<p><\/p>\n\n\n\n<p>We offer a comprehensive genomic imputation service using THL Biobank\u2019s SISu reference panel.<\/p>\n\n\n\n<p><strong>Do you have genetic variation data collected from Finns?<\/strong> Our service can complete your data by imputing missing genotypes based on the Finnish haplotype reference panel SISu v3, making your data ready for genetic association studies and other analyses.<\/p>\n\n\n\n<p><strong>Why choose the Finnish haplotype reference panel?<\/strong><br>\u2022 Improved Accuracy: It enhances the accuracy of genomic analysis<br>\u2022 Increased Power: It boosts the power of genome-wide association studies<br>\u2022 Fine-Mapping Enhancement: It improves fine-mapping of genetic data<br>\u2022 Meta-Analysis and Integration: It enables seamless meta-analysis and integration with other studies<\/p>\n\n\n\n<p><strong>Imputation Reference Panel Details:<\/strong><br>We utilize the THL Biobank\u2019s SISu v3 haplotype reference panel, which is derived from high-coverage whole-genome sequence data of 1,768 Finns. For a detailed description of the reference panel, please refer to the <a href=\"https:\/\/thl.fi\/en\/research-and-development\/thl-biobank\/for-researchers\/sample-collections\/thl-biobank-imputation-reference-panel\">documentation<\/a>.<\/p>\n\n\n\n<p><strong>Application process:<\/strong><br>If you are interested in our imputation service, please contact us via bioinformatics@uef.fi and apply for permission to use the imputation panel from THL. The application process is described in detail on the <a href=\"https:\/\/thl.fi\/en\/research-and-development\/thl-biobank\/for-researchers\/application-process\/thl-biobank-application-portal\">website<\/a>. After logging in to the application portal choose: \u201d5. OTHER COLLECTION: THL Biobank Imputation reference panel\u201d.<\/p>\n\n\n\n<p><em><strong>Note:<\/strong> we are currently using SISu v4 reference panel!<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"<p>We offer a comprehensive genomic imputation service using THL Biobank\u2019s SISu reference panel. Do you have genetic variation data collected from Finns? Our service can complete your data by imputing missing genotypes based on the Finnish haplotype reference panel SISu v3, making your data ready for genetic association studies and other analyses. Why choose the [&hellip;]<\/p>\n","protected":false},"author":991,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-697","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.6 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Genomic Imputation Service - UEF Bioinformatics Center<\/title>\n<meta name=\"description\" content=\"SISu imputation for genotype data from Finnish samples, using the THL Biobank reference panel. 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