{"version":"1.0","provider_name":"Lehtonen lab\/ Human Brain Disease Modelling Research Group","provider_url":"https:\/\/sites.uef.fi\/human-brain-disease-modelling-group","title":"Microglia in \u03b1-synucleinopathies - Lehtonen lab\/ Human Brain Disease Modelling Research Group","type":"rich","width":600,"height":338,"html":"<blockquote class=\"wp-embedded-content\" data-secret=\"UHTvwVhVBr\"><a href=\"https:\/\/sites.uef.fi\/human-brain-disease-modelling-group\/microglia-in-%ce%b1-synucleinopathies\/\">Microglia in \u03b1-synucleinopathies<\/a><\/blockquote><iframe sandbox=\"allow-scripts\" security=\"restricted\" src=\"https:\/\/sites.uef.fi\/human-brain-disease-modelling-group\/microglia-in-%ce%b1-synucleinopathies\/embed\/#?secret=UHTvwVhVBr\" width=\"600\" height=\"338\" title=\"&#8220;Microglia in \u03b1-synucleinopathies&#8221; &#8212; Lehtonen lab\/ Human Brain Disease Modelling Research Group\" data-secret=\"UHTvwVhVBr\" frameborder=\"0\" marginwidth=\"0\" marginheight=\"0\" scrolling=\"no\" class=\"wp-embedded-content\"><\/iframe><script type=\"text\/javascript\">\n\/* <![CDATA[ *\/\n\/*! This file is auto-generated *\/\n!function(d,l){\"use strict\";l.querySelector&&d.addEventListener&&\"undefined\"!=typeof URL&&(d.wp=d.wp||{},d.wp.receiveEmbedMessage||(d.wp.receiveEmbedMessage=function(e){var t=e.data;if((t||t.secret||t.message||t.value)&&!\/[^a-zA-Z0-9]\/.test(t.secret)){for(var s,r,n,a=l.querySelectorAll('iframe[data-secret=\"'+t.secret+'\"]'),o=l.querySelectorAll('blockquote[data-secret=\"'+t.secret+'\"]'),c=new RegExp(\"^https?:$\",\"i\"),i=0;i<o.length;i++)o[i].style.display=\"none\";for(i=0;i<a.length;i++)s=a[i],e.source===s.contentWindow&&(s.removeAttribute(\"style\"),\"height\"===t.message?(1e3<(r=parseInt(t.value,10))?r=1e3:~~r<200&&(r=200),s.height=r):\"link\"===t.message&&(r=new URL(s.getAttribute(\"src\")),n=new URL(t.value),c.test(n.protocol))&&n.host===r.host&&l.activeElement===s&&(d.top.location.href=t.value))}},d.addEventListener(\"message\",d.wp.receiveEmbedMessage,!1),l.addEventListener(\"DOMContentLoaded\",function(){for(var e,t,s=l.querySelectorAll(\"iframe.wp-embedded-content\"),r=0;r<s.length;r++)(t=(e=s[r]).getAttribute(\"data-secret\"))||(t=Math.random().toString(36).substring(2,12),e.src+=\"#?secret=\"+t,e.setAttribute(\"data-secret\",t)),e.contentWindow.postMessage({message:\"ready\",secret:t},\"*\")},!1)))}(window,document);\n\/\/# sourceURL=https:\/\/sites.uef.fi\/human-brain-disease-modelling-group\/wp-includes\/js\/wp-embed.min.js\n\/* ]]> *\/\n<\/script>\n","description":"Microglia phagocytose \u03b1-synuclein aggregates which leads to release of proinflammatory cytokines, and in contrast, we have shown that presence of these cytokines may inhibit phagocytosis of aberrant proteins by human microglia (Niskanen et al., 2024). This causes inflammatory damage to neighbouring cells, leading to fewer microglia being able to take up and degrade \u03b1-synuclein, resulting [&hellip;]","thumbnail_url":"https:\/\/sites.uef.fi\/human-brain-disease-modelling-group\/wp-content\/uploads\/sites\/286\/2025\/02\/image.png","thumbnail_width":1047,"thumbnail_height":636}