{"id":184,"date":"2020-06-12T09:18:12","date_gmt":"2020-06-12T06:18:12","guid":{"rendered":"https:\/\/sites.uef.fi\/humea\/?page_id=184"},"modified":"2020-06-30T13:56:30","modified_gmt":"2020-06-30T10:56:30","slug":"epm1-eco","status":"publish","type":"page","link":"https:\/\/sites.uef.fi\/humea\/projects\/epm1-eco\/","title":{"rendered":"EPM1-Eco"},"content":{"rendered":"<h1>EPM1-Eco<\/h1>\n<p>EPM1-Eco-project is a part of the New Modalities Ecosystem (<a href=\"https:\/\/www.businessfinland.fi\/en\/whats-new\/news\/2018\/creation-of-novel-medicines-and-better-patient-care-for-the-future-in-an-ecosystem\/\">https:\/\/www.businessfinland.fi\/en\/whats-new\/news\/2018\/creation-of-novel-medicines-and-better-patient-care-for-the-future-in-an-ecosystem\/<\/a>) that was built by Orion Pharma in year 2018. The ecosystem participants include several universities (University of Eastern Finland, University of Helsinki, University of Turku and Folkh\u00e4lsan) and companies (Orion Pharma, PerkinElmer, Syrinx Bioanalytics, AdmeScope, Petsofi, Forendo Pharma and InMe). The aim of the ecosystem is to improve the understanding of disease pathology related to symptoms and disease progression and to discover better drug treatments and diagnostic tools as well as digital wearable recording methods for symptom evaluation.<\/p>\n<p>EPM1-Eco-project focuses on developing wearable home-based monitoring for progressive myoclonus-epilepsy (EPM1), that is a progressive disease characterized by stimulus-sensitive myoclonus (muscle jerks) and tonic-clonic epileptic seizures.<\/p>\n<p>In the patient study in collaboration between the Kuopio University Hospital and the University of Eastern Finland, home-based monitoring will tested for quantifying disease characteristics in EPM1. Algorithms will be developed for extracting myoclonic features from surface electromyographic (EMG) and motion data. The connection of continuous EMG and kinematic data with TMS, TMS-EEG and PET will be studied.<\/p>\n<p>The person in charge of the patient study is Reetta K\u00e4lvi\u00e4inen (Professor of Neurology, University of Eastern Finland and Director of Kuopio Epilepsy Center, Kuopio University Hospital).<\/p>\n<p>More information about the development of wearable monitoring tools and analysis algorithms are given by:<\/p>\n<p><a href=\"https:\/\/uefconnect.uef.fi\/en\/person\/saara.rissanen\/\" target=\"_blank\" rel=\"noopener noreferrer\">Saara Rissanen<\/a><\/p>\n<p><a href=\"https:\/\/uefconnect.uef.fi\/en\/person\/pasi.karjalainen\/\" target=\"_blank\" rel=\"noopener noreferrer\">Pasi Karjalainen<\/a><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"size-medium wp-image-187 alignleft\" src=\"https:\/\/sites.uef.fi\/humea\/wp-content\/uploads\/sites\/40\/2020\/06\/bf_logo_blue_rgb-300x128.jpg\" alt=\"\" width=\"300\" height=\"128\" srcset=\"https:\/\/sites.uef.fi\/humea\/wp-content\/uploads\/sites\/40\/2020\/06\/bf_logo_blue_rgb-300x128.jpg 300w, https:\/\/sites.uef.fi\/humea\/wp-content\/uploads\/sites\/40\/2020\/06\/bf_logo_blue_rgb-1024x436.jpg 1024w, https:\/\/sites.uef.fi\/humea\/wp-content\/uploads\/sites\/40\/2020\/06\/bf_logo_blue_rgb-768x327.jpg 768w, https:\/\/sites.uef.fi\/humea\/wp-content\/uploads\/sites\/40\/2020\/06\/bf_logo_blue_rgb.jpg 1193w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/p>\n","protected":false},"excerpt":{"rendered":"<p>EPM1-Eco EPM1-Eco-project is a part of the New Modalities Ecosystem (https:\/\/www.businessfinland.fi\/en\/whats-new\/news\/2018\/creation-of-novel-medicines-and-better-patient-care-for-the-future-in-an-ecosystem\/) that was built by Orion Pharma in year 2018. The ecosystem participants include several universities (University of Eastern Finland, University of Helsinki, University of Turku and Folkh\u00e4lsan) and companies (Orion Pharma, PerkinElmer, Syrinx Bioanalytics, AdmeScope, Petsofi, Forendo Pharma and InMe). The aim of the [&hellip;]<\/p>\n","protected":false},"author":81,"featured_media":0,"parent":148,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"class_list":["post-184","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.1.1 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>EPM1-Eco - HUMEA Lab &amp; BSAMIG research group<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/sites.uef.fi\/humea\/projects\/epm1-eco\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"EPM1-Eco - HUMEA Lab &amp; BSAMIG research group\" \/>\n<meta property=\"og:description\" content=\"EPM1-Eco EPM1-Eco-project is a part of the New Modalities Ecosystem (https:\/\/www.businessfinland.fi\/en\/whats-new\/news\/2018\/creation-of-novel-medicines-and-better-patient-care-for-the-future-in-an-ecosystem\/) that was built by Orion Pharma in year 2018. The ecosystem participants include several universities (University of Eastern Finland, University of Helsinki, University of Turku and Folkh\u00e4lsan) and companies (Orion Pharma, PerkinElmer, Syrinx Bioanalytics, AdmeScope, Petsofi, Forendo Pharma and InMe). 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The ecosystem participants include several universities (University of Eastern Finland, University of Helsinki, University of Turku and Folkh\u00e4lsan) and companies (Orion Pharma, PerkinElmer, Syrinx Bioanalytics, AdmeScope, Petsofi, Forendo Pharma and InMe). 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