Program

DPMM Winter School 2023

12.05.2023 University of Eastern Finland – Snellmania – Kuopio

8:15 – 8:30 Opening words [Katja Kanninen (DPMM vice chair) & Jenni Küblbeck (DPMM coordinator)]

8:30 – 9:00 Keynote lecture (Eino Solje, Director of UEF Brain Research Unit)

9:00 – 9:50 Session I – oral presentations / poster pitches (SN100) [Chairs: Pracheta De, Elena Ppali]
- 9:00 – 9:10 Sohvi Ohtonen (Impact of diesel-exhaust derived air pollution on transcriptome and functionality of iPSC-derived microglia)
- 9:10 – 9:20 Tomi Hietanen (Effects of C9orf72 hexanucleotide repeat expansion on the function of FTD patient-derived iPSC-microglia)
- 9:20 – 9:30 Juha Valjakka (Correlation of MB-SWIFT fMRI with neuronal activity during sensory stimulation in anesthetized and awake rats)
- 9:30 – 9:40 Lenka Dvoráková (Association of thalamic neuroinflammation and the functional connectivity in a rat model of traumatic brain injury – a longitudinal study)
- 9:40 – 9:50 Aravinth Ravichandran (Hyperpolarized metabolic magnetic resonance imaging of cerebral ischemia at low magnetic field) [poster pitch]
- 9:45 – 9:50 Buddika Jayasingha (A deep learning approach for identification of metabolic states in leukemia cells) [poster pitch]

9:50 – 11:00 Poster Session I / Coffee and sponsor exhibition (SN lobby) [Odd numbered posters]

11:00 – 11:50 Session II – oral presentations / sponsor talks (SN100) [Chairs: Sini Pitkänen, Jonna Niskanen]
- 11:00 – 11:10 Mustafa Beter (SproutAngio: An Open-Source Bioimage Informatics Tool for Quantitative Analysis of Sprouting Angiogenesis and Lumen Space)
- 11:10 – 11:20 Sonja Koivukoski (Unstained tissue imaging and virtual HE-staining of histological whole slide images: an assessment of histological feasibility)
- 11:20 – 11:30 Mireia Gómez-Budia (Spiked up microglia-containing neural organoid model)
- 11:30 – 11:40 Sponsor talk – Finnadvance (Highly scalable and automation compatible organ-on-chip platforms for relevant in vitro models)
- 11:40 – 11:50 Sponsor talk – Kuopio Center for Gene and Cell Therapy (KCT) (What do we do at KCT Oy)

13:20 – 14:10 Session III – oral presentations / poster pitches (SN100) [Chairs: Sohvi Ohtonen, Ahmed Mohamed]
- 13:20 – 13:30 Roosa Kaarijärvi (DPYSL5 is Highly Expressed in treatment-induced Neuroendocrine Prostate Cancer and Promotes Cellular Stemness Through Activation of Polycomb Repressive Complex 2)
- 13:30 – 13:40 Kirsi Kainulainen (M1 macrophages drive prostate cancer stem cell plasticity by stimulating the expression of NANOG, SOX2 and CD44)
- 13:40 – 13:50 Kaisa Mäki-Mantila (Hyaluronan coated extracellular vesicles from melanoma cells promote mixed M1/M2 phenotype on macrophages)
- 13:50 – 14:00 Sanni Moisio (KRAS deletions are associated with fast treatment response in ETV6::RUNX1 leukemia)
- 14:00 – 14:05 Johannes Hiltunen (Oncogenic versus tumor suppressive actions of glucocorticoid receptor in prostate cancer) [poster pitch]
- 14:05 – 14:10 Bharadwaja Velidendla (Transcriptional regulation of anti-inflammatory glucocorticoid signaling) [poster pitch]

14:10 – 15:20 Poster Session II / Coffee and sponsor exhibition (SN lobby) [Even numbered posters]

15:20 – 15:50 DPMM Board – panel discussion (SN100) [Chair: Jenni Küblbeck (DPMM coordinator)]

15:50 – 16:30 Session IV – oral presentations (SN100) [Chairs: Tomi Hietanen, Meheli Banerjee]
- 15:50 – 16:00 Tanja Turunen (Cell-type-specific characterization of miRNA gene dynamics in immune cell subpopulations during aging and atherosclerosis disease progression at single-cell resolution)
- 16:00 – 16:10 Valeria Iannone (Aldafermin-producing Escherichia coli Nissle 1917 improved metabolic pathways of non-alcoholic fatty liver disease murine model)
- 16:10 – 16:20 Sini Pitkänen (Functional effects of phthalates in vitro and in vivo)

16:20 – 16:40 Introduction of UEF Doctoral researchers’ association [ItaVa] (SN100) Lenka Dvoráková

16:40 – 16:50 Closing and Best DPMM thesis for 2022 (SN100) [Katja Kanninen (DPMM vice chair) & Jenni Küblbeck (DPMM coordinator)]