Facilities

Facilities

Kuopio BIU equipment consist of four MRI scanners, PET/MRI, μCT and μPET unit, optical, ultrasound and photo acoustic small animal imaging. For MRI most of the contemporary imaging and spectroscopy pulse sequences are available or can be implemented on request. μPET imaging is done in collaboration with Kuopio University Hospital and with its radiochemistry laboratory and cyclotron. Through this collaboration PET imaging with tailor made radiopharmaceuticals can be attained.

 

7T Bruker & 9.4T Varian & 9,4T Bruker/Varian

MRI

Kuopio Biomedical Imaging Unit houses five experimental MRI scanners operating from 0.7 T to 11.7T:

    • 9.4 T/31 cm horizontal MRI magnet (Agilent DirectDrive, VNMRj 3.1 and OpenVNMRj, and Bruker Biospec, PV 5.1 and 6.01) with 1H and X channels : Animals up to rabbits
    • 7 T/16 cm horizontal Bruker PharmaScan (PV 5.1 and 6.01) magnet : Animals up to rats
    • Horizontal simultaneous PET/MRI system with variable field strength (0.7 T, 3 T or 7 T)/16 cm and 1H and X channels (MR Solutions) : Animals up to rats
    • Vertical 9.4 T/89 mm magnet (Agilent DirectDrive, VNMRj 3.1) : Animals up to mice, tissues
    • Vertical 11.7 T/20 mm magnet (Bruker MicroImaing, PV 6.0.1) with 1H and X channels : Materials, cells and tissues

Hypermag

Hyperpolariser

Pre-clinical Hyperpolariser, SpinAligner (from The Technical University of Denmark), with adjustable polarisation field 3.35-10.1 T and automated dissolution system capable of providing samples up to tens of ml. Currently situated next to 9.4 T horizontal imaging magnet.


PET/MRI

Pre-clinical PET/MRI system, MR Solutions DRYMAG 7024 with PET insert, allows simultaneous imaging of one rat or up to three mice. System also has variable field and a cryoprobe.


Inveon DPET

PET

With the Inveon Dedicated PET (Siemens) up to two rats or 4 mice can currently be imaged with PET simultaneously. The detector ring consists of lutetium oxyorthosilicate  (LSO) block detectors, with 10 cm transaxial and 12.7 cm axial field-of-view and reaching 1.3 mm resolution. It is mainly used for imaging with various biomolecules labeled with e.g. 18F, 11C or 89Zr.


(Picture TBA)

MicroCT

The MILabs U-CTUHR provides high-resolution in vivo anatomical imaging. The unit is suitable for imaging mice and rats. The CT unit has 7 µm focal spot size, maximum transaxial field-of-view of 13.5 cm and resolution of down to 15µm in focus mode. The voltage range of X-Ray tube is 10-65 kV.