Research Areas

NOVEL Postdoctoral Programme offers research possibilities in four research areas: Prevention and Care; Methods and Data; Innovation and Society; and Ethics and Well-being. You will define your own research topic within these four broad areas.

NOVEL research areas
NOVEL research areas

We target diverse talents and a variety of brain health research perspectives. We welcome researchers from diverse social, cultural and disciplinary backgrounds, and accommodate interdisciplinary research designs.

We are recruiting Postdoctoral Researchers into two research areas per call. The first call focuses on the research areas of Prevention and Care as well as Methods and Data. The second call focuses on the research areas of Innovation and Society as well as Ethics and Wellbeing.

Call 1: March 2025-May 2025

Nine positions are open in the first call in two research ares: Prevention and care and Methods and data.

Research Area 1 and 2: Prevention and Care & Methods and Data

Both genetics and environmental factors contribute to brain diseases, with environmental and lifestyle factors significantly influencing their global burden. In addition to genetics contributing to the disease risk, we emphasize the importance of environmental and lifestyle factors. Effective prevention will require integrating large exposure datasets, multi-omics, imaging, epigenetics, and advanced data analytics to uncover biomarkers, assess disease risk and suitability of treatments. This knowledge will support better personal lifestyle choices, identify therapeutic targets, reduce healthcare costs, and guide regulatory efforts to protect public health.

We also actively develop human-based disease models and technologies related to the use of human brain tissue samples. iPSC technologies, patient brain biopsies and resections, and novel human-based cellular models will be used to study genetic, lifestyle, and environmental factors in brain disorders. These efforts are complemented by studies on living human brain material using electrophysiology, single-cell technologies, and omics approaches to bridge preclinical findings with clinical applications.

By integrating human-based models and advanced methodologies, we aim to uncover disease mechanisms, identify therapeutic targets, and develop novel diagnostic and prognostic tools. Approaches include omics-based analyses (transcriptomics, epigenomics, proteomics), imaging, behavioral studies, deep phenotyping, electrophysiology, histopathology, and AI-driven neuroinformatics, enabling personalized insights into brain disorders. We actively develop new AI-based approaches to answer the needs in analyzing and integrating heterogenous brain data originating from a variety of sources and measurements.

Research Groups in These Areas

Here you can find the research group descriptions for the research areas Innovation in society and Ethics and wellbeing including information about the leader(s) of the group, faculty, group composition, and the group’s contact details. The group descriptions are in alphabetical order.

Call 2: November 2025-January 2026

5 positions are open in the second call in the research areas of Innovation in society and Ethics and wellbeing.

Research Areas 3 and 4: Innovation in Society & Ethics and Wellbeing

This call focuses on two research areas: Innovation in society and Ethics and wellbeing. Within these areas, we examine how brain health can be understood, supported, and improved from diverse social and economic perspectives. Our research addresses the socio-legal-economic dimensions of brain health innovation, while also exploring broader questions around ethics and wellbeing, as well as societal and economic impact.

We investigate how challenges, such as neurological disorders and mental health issues can be addressed through innovations, systems, policies, and laws that prioritise accessibility, fairness, and effectiveness. This includes examining the role of new products, services, and companies, as well as preventive measures, care paths and treatments, in improving outcomes by focusing on ethics, wellbeing, and cost-effectiveness. In these contexts, we explore Public and Patient Involvement (PPI), patient rights, and access to services and care, including the cultural, social, and economic forces guiding these activities.

By integrating perspectives from innovation research, health economics, and legal studies, we provide insights into solutions that deliver tangible value and societal impact. We are further interested in how specific brain health issues and solutions influence individuals, communities, and societies. Our research highlights existing inequalities and offers actionable strategies to make health and social care systems more inclusive. Also, we aim to ensure that health research, development, and innovation (RDI) practices and processes are responsive and supportive for diverse populations.

Our research is grounded in a wide range of research methods, including interviews, surveys, and registry data analysis, alongside participatory and co-research strategies. We also offer possibilities to use existing data sets (e.g., SHARE Home) to create new knowledge and robust evidence. By evaluating the potential of novel, inspiring approaches, we support brain health solutions that are not only effective but also equitable and deeply rooted in the lived experience of citizens, patients, and caregivers.

For further details, see descriptions of the research groups and supervisors.

Research Groups in These Areas

Here you can find the research group descriptions for the research areas Innovation in society and Ethics and wellbeing including information about the leader(s) of the group, faculty, group composition, and the group’s contact details. The group descriptions are in alphabetical order.

Research Infrastructure

UEF has state-of-the-art infrastructure for neuroscience driven research, and all facilities are included and partly funded by Biocenter Kuopio (BCK). The core infrastructures include:

  • Neurodata infrastructure
  • Stem Cell/iPSC Core Facility
  • In Vitro and Ex Vivo Electrophysiology Core Facility
  • Kuopio Biomedical Imaging Unit
  • Brain Research Unit
  • Biomarker Laboratory
  • Phenotyping Center, Neurophenotyping Unit

Other key infrastructures include:

  • Genome Center of Eastern Finland
  • Biobank of Eastern Finland
  • Lab Animal Center
  • Clinical Research Center
  • Cell and Tissue Imaging Unit
  • National Virus Vector Laboratory
  • In Vitro and In Vivo Imaging Center
  • SIB Labs
  • LS-MS Metabolomics Center
  • YHKA and Business School Facility
  • Kuopio University Hospital infrastructures include KUH Data Lake and PET/MRI imaging at KUH Imaging Centre.

Human cohorts (e.g., AD cohorts ADGEN and UEF-BRAIN; population-based cohorts FINGER and CAIDE; large EpiBiomarker-cohort, NPH cohort, clinical FTD cohort, EADB; appr. 500 000 patients and control samples) have been collected and extensively used for assessing genetic background of diseases, multidomain intervention, clinical trials and discovery and longitudinal validation of biomarkers. Many of these cohorts are transferred to the Biobank of Eastern Finland, which allows to increase the amount of personalized genetic data via the GWAS-based screenings as a part of the ongoing FinnGen research project, focusing on global genetic screening of 500 000 individuals in Finland.

A data lake is a centralized repository that allows to run a large spectrum of analyses – from dashboards and visualizations to big data processing, real-time analytics, and machine learning to guide better decisions. Conversely, “registromics” -based platforms and IT solutions will enable to connect multiple outcome registries (e.g., KELA and THL) with different biomedical data sources and enable to conduct reversed data mining.

Open Science and Co-research

Open science practices are implemented as an integral part of the NOVEL programme following the Horizon Europe, MSCA and UEF Open Science policy programs on “as open as possible as closed as necessary” principle. Our researchers receive training on open Science and data management.

NOVEL promotes:

  1. early, open sharing of research through pre-registration, pre-prints and crowd sourcing
  2. open sharing of data, software, algorithms and workflows through deposition in trusted repositories
  3. participation in open peer-review, and publication venues that use open peer-review
  4. involving end-users in co-creation through the stakeholder networks. 

According to the UEF policy, peer-reviewed publications will be open access. The Finnish universities have joint contracts with all major publishers on open access publishing free of charge. In addition, UEF library automatically makes all publications available in the open access UEF E-repository (UEF eRepo). UEF provides financial support for open access publishing in journals meeting the ranking criteria and research groups allocate additional funding for open access publishing.

Our researchers will prepare a Data Management Plan explaining how their research will comply with the FAIR (Findable, Accessible, Interoperable, and Reusable) principles. In the spirit of NOVEL, all our reseachers have the opportunity to involve all relevant knowledge actors in their research, and thus involve citizens, patient advocacy groups and business actors in co-research practices.